Mirhan Mohamed Khader, Hala Kamal Abdel Gaber And Ahmed Elsayed Hamed Am,

ABSTRACT


Aim: The Assessment Of Relationship Between Peri-implant Sulcular Fluid (PISF) Cytokines Level (lL-1~ &TNF-a) And The Condition Of Peri-implant Tissue In Obese Patients (primary Objective). The Clinical And Radiographic Evaluation Of The Impact Of Obesity On Peri-implant Tissues (secondary Objective) .. Subjects And Methods: Twenty Patients Were Included In The Study For Placement Of A Delayed Implant In Lower Molar Area. They Were Divided Into Two Groups, Ten Obese Patients And Ten Normal Weight Patients. TNF-a And IL-1 ~ Were Measured Using ELISA Kits, While Bone Level Measurement Using Cone Beam CT And Clinical Parameters Were Also Assessed.

Results: Regarding Clinical Findings (bleeding Index, Plaque Index, Probing Depth) In Both Groups, In Case Of Intragroup Comparison Wilcoxon Signed Rank Test Was Used And It Revealed No Significance Difference And, In Case Of Intergroup Comparison A Mann Whitney U Test Was Used And It Also Revealed No Significant Difference. Regarding Peri-implant Crestal Bone Changes, The Percent Of Change Throughout The Study In The Obese Group Recorded A Median Of 0.4, While Non-obese Group Recorded A Median Of -0.52. Mann Whitney U Test Revealed That The Difference Between The 2 Groups Was Not Statistically Significant. Regarding Tumor Necrosis Factor, In The First And Second Assessment Independent T Test Revealed That The Difference Between Obese And Non-obese Was Not Statistically Significant. The Percent Change OfTNF-a Values Throughout The Study In The Obese Group Recorded A Median Of -22.61 %, While Non-obese Group Recorded A Median Of -32.43%. Mann Whitney U Test Revealed That The Difference Between The 2 Groups Was Not Statistically Significant. Regarding Interleukin 1-~, In The First And Second Assessment Independent T Test Revealed That The Difference Between Obese And Non-obese Was Not Statistically Significant. Conclusion Within The Limitations Of Our Study We Can Conclude That: 1. Obesity Can Exert No Effect On Peri-implant Tissue Status In The Absence Of Dental Plaque. 2. Obesity Can Lead To Slight Elevation In Inflammatory Markers (TNF-a And IL-1~) In Peri-implant Sulcular Fluid Which May Be To A Subclinical Level That Have No Effect On Clinical Parameters Of Gingival Inflammation As Long As Plaque Control Is Applied.